Eculizumab yog monoclonal antibody

Lus Askiv Lub Npe: Eculizumab

Tus lej lej: 219685-50-4

Molecular Chiv:

Molecular hnyav: 0

{{0} ine einecs tus lej:

Lwm yam kev siv tshuaj: cov tshuaj yeeb; Mab 10; Tshuaj Nplaum Xov Xwm

Cov Mol Cov Ntaub Ntawv: MOL cov ntaub ntawv

Cov Qauv Txheej Txheem:

Tosizuzum Cov Khoom Siv

Kev Cia Cov Neeg Tiv Thaiv: Khw ntawm -20 c

Daim Ntawv: Ua Kua

Xim: tsis muaj xim daj rau daj daj

CAS database: 219685-50-4

Cov lus qhia luv luv

FDA pom zoo raucizumab hauv cov neeg laus nrog kev mob caj dab, uas yog mob Tshaj dhau los kaum xyoo dhau los, tshuaj lom neeg muaj ntau yam kab mob-tshem tawm cov tshuaj antirheumatic tau pom zoo rau kev ua lag luam. Cov tshuaj no tsom cov txheej txheem tiv thaiv kab mob ntawm kev mob ntsws, thiab tau raug ua kom muaj kev puas tsuaj rau cov neeg mob, yog li lawv tau txhim kho cov txiaj ntsig zoo ntawm tus kabmob.

Pharmacological txiav txim siab

Ntxiv rau kev koom tes rau cov qog ua haujlwm necrososeces ntawm cov txheej txheem Rheumatoid yog cuam tshuam nrog lwm cov kev ua haujlwm siab, xws li {}} {2}}. Ntawm lawv, Ipt -6 yog ib lub luag haujlwm plectokine uas ua rau cov txheej txheem biological nrog cov kev tswj hwm ntawm kev tiv thaiv kab xeb thiab cov txheej txheem thev naus laus zis. Kos npe los ntawm il -6}} Puas yog kho kho kom zoo nkauj muaj protein}} r) thiab kos npe rau membrane. Ib soluble il -6 r (sll 6 r) rov qab rau GP 130 tom qab khi rau cov xwm txheej. TOSCUMAB (eculizuminjection) muaj peev xwm khi tau tshwj xeeb rau sll {}}} r thiab r-mediated {} {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {18 {.

Kev taw tes

TOSCUMAB (eculizumin txhaj) yog siv los kho paroxysmal pw tsaug zog hemoginuria (Ahus hemolytic uremic surement (ahus) hauv cov neeg laus thiab menyuam yaus.

Pharmaconinetics

TOSCUMAB (eculizuminjection) yog Manoclonal Monoclonal IGG antibodody uas khi rau protein ua kom tiav rau C5A thiab C5B. Tiv thaiv kev tsim cov C5B inhibited ua rau tsim tom ntej ntawm lub davhlau ya nyob twg c5B {5}} lossis Mac. Intraloscular handolysis nrog lub davhlau ya nyob nrog kev ua kom zoo nkauj yog qhov chaw kho mob tseem ceeb ntawm paroxysmal nocturnal hemoglobinuria (pnh). Thaiv kev tsim ntawm daim nyias nyias nres ua rau hemoglobin ruaj khov thiab txo qhov xav tau ntawm RBC hloov pauv. Qhov tsis pom kev cai ntawm kev ua haujlwm ua tiav hauv kev tswj tsis tau ua tiav kev ua haujlwm hauv atypical hemolytic surementic suremdrome (AHUS).

Daim Ntawv Thov Cheeb Tsam

FDA Pom zoo Tosizumab rau cov neeg laus uas muaj kev pom zoo rau kev mob siab rau Raum, uas tau pom zoo ua ntej Thaum lub Plaub Hlis 2008, Tosizumab tau txais qhov kev kho mob tshiab ntawm kev kho mob ntsws, kev ua mob caj dab me me TOSCUMAB (EMULLIUMABCE)

Sab cuam

ToCilIzumab feem ntau zoo rau siab, thiab cov kev mob hnyav tshaj plaws rau nws txoj kev kho mob suav nrog kev ua haujlwm hauv tsev kho mob thiab kev mob plab zom mov. Hauv kev tshawb fawb soj ntsuam, feem ntau cov kev tshwm sim tshwm sim ntawm TOSIZumab tau raug mob sab saud, thiab kom siab rau lub siab lub siab transaminase. Qhov nce hauv lub siab transivinese ntau feem ntau yog nyob rau hauv cov me thiab tau thim rov qab thiab tsis coj mus rau qhov tseem ceeb lossis kuaj pom kev ua pov thawj. Kev Kho Mob Tosizumab kuj tau ua rau muaj kev nce me me hauv tag nrho cov roj (cholesterol) tag nrho cov roj (cholesterol)

Cov Ntaub Ntawv Seev Cev

Cov ntaub ntawv muaj tshuaj lom: 219685-50-4 (cov khoom muaj kev phom sij)

Cim npe nrov: allulizumab yog monoclonal antibody, Tuam Tshoj eculizumab yog monoclonal tshuaj tiv thaiv tshuaj tiv thaiv